Tuesday, April 30, 2013

Protein shaped like a spider

Monday, April 29, 2013

The protein C4BP is similar to a spider in its spatial form with eight "arms". The structure of the "spider body" has recently been described in detail by researchers from the Helmholtz Centre for Infection Research (HZI) in Braunschweig and the Technische Universit?t Darmstadt. This leads the scientists to unconventional ideas ? the protein is possibly suitable as a scaffold for the transport of active pharmaceutical substances, particularly biomolecules. The researchers are publishing their results in the current edition of the international journal Journal of Molecular Biology.

The so-called complement system is a part of the innate immune defence within the human body: more than sixty different proteins form one of the first countermeasures against invading pathogens. One of them is the C4b binding protein known as C4BP. It is involved in the immune defence against bacteria in the blood. How precisely such protein substance carries out its function or how it interacts with other molecules ? this can only be predicted by scientists once they have identified the spatial structure of the molecule. Structural biologists therefore examine the substance in its purest form with x-ray machines and are able to reconstruct the spatial design in a computer. Regarding the case of the recently-described C4BP, they found out that it has eight "arms" and thus resembles a spider to a certain degree. Seven of the "arms" are identical as "alpha chains", while the eighth, a "beta chain" is different from the others. The spider body that holds these side chains together is called the oligomerisation domain. Its structure was of special interest to researchers, since it determines the spatial alignment of the "arms".

The newly-described structure allows two possible variants. "However, there is one of these two possibilities that is more feasible because it is much more stable", says Thomas Hofmeyer, PhD student at the Institute for Organic Chemistry and Biochemistry of TU Darmstadt and first author for the publication. And the C4BP is quite stable, as explained by the other first author Dr. Stefan Schmelz from the Department of Molecular Structural Biology of HZI: "Even boiling is not able to break down its form." Usually, human proteins remain stable up to about 40?C. Higher temperatures are of course not found in the body, but the stability of C4BP has a completely different purpose: "As is the case with all components of the complement system, the C4b binding protein is present in blood plasma. The proteins are exposed to enormous shear forces in the blood stream", explains Dr. Andrea Scrima, head of the junior research group "Structural Biology of Autophagy" at HZI. Therefore, the protein needs a high stability in order to be able to withstand these forces.

The researchers now would like to make use of the spatial structure. Their discoveries have facilitated biochemical synthesis of the molecule. In the context of replication within a test tube, the researchers can undertake alterations in a targeted way: "Instead of the seven alpha chains, we could implement other biomolecules", claims Prof. Harald Kolmar, director of the work group Applied Biochemistry at the Institute for Organic Chemistry and Biochemistry at the Technische Universit?t Darmstadt. "We can use the oligomerisation domain as a framework, in order to decorate it with drug molecules." These could be vaccines, for example. Seven with one stroke, by means of the seven-fold binding capability. Bundled in this manner, more active ingredient could make its way to its target. The dosage could be reduced but the immune system would still be considerably stimulated. "It is thereby possible in the future that bottlenecks, limiting the supply of vaccine, could be avoided and side effects reduced", says Kolmar.

###

Thomas Hofmeyer*, Stefan Schmelz*, Matteo T. Degiacomi, Matteo Dal Peraro, Matin Daneschdar, Andrea Scrima, Joop van den Heuvel, Dirk W. Heinz, Harald Kolmar, * contributed equally Arranged Sevenfold: Structural Insights into the C-Terminal Oligomerization Domain of Human C4b-Binding Protein Journal of Molecular Biology, 2013, DOI: 10.1016/j.jmb.2012.12.017

Helmholtz Centre for Infection Research: http://www.helmholtz-hzi.de/en

Thanks to Helmholtz Centre for Infection Research for this article.

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Source: http://www.labspaces.net/127972/Protein_shaped_like_a_spider

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The business case for monarchies - Fortune Management

By Jeroen Ansink

Queen Beatrix and Crown Prince Willem Alexander of The Netherlands

Dutch King Willem-Alexander and his mother, recently abdicated Queen Beatrix

FORTUNE ? It's good to be the king. But, when it comes to a nation's economic health, it's also good to have a king ? or queen ? on hand. Monarchs open economic doors.

"In the presence of royalty, companies can enter circles they wouldn't be able to get in by themselves," says Ang?lique Heijl, deputy director of international economic affairs at VNO-NCW, the largest employers' organization in the Netherlands. "This holds particularly true for countries where the government plays a large role in the economy."

Monarchs typically serve their respective nations longer than democratically elected heads of state: the recently abdicated Dutch Queen Beatrix was on the throne for 33 years, Elizabeth II of Britain has held her position for 61 years and counting. This kind of leadership stability gives these particular figures additional sway in the business community.

"The presence of the queen gives a mission just a little bit more cachet," says Erik Oostwegel, vice-chair at engineering consultancy Royal HaskoningDHV, who joined Queen Beatrix on visits to Oman, Qatar, and the UAE.

MORE: Offshore account holders win a victory in government tax case

While the impact of these visits is hard to quantify, they do generate cultural, political, and economic benefits, says architect Ben van Berkel, whose agency UNStudio went along on a royal trip to Singapore. "For companies who already have established contacts, an essential benefit is that your clients become aware that you have royal and political support in your own country. This is extremely beneficial in generating trust."

"The use of the Queen, in a dignified capacity, is incalculable," wrote the 19th-century British businessman and editor-in-chief of The Economist Walter Bagehot in The English Constitution.

In a 2007 study, Harry van Dalen, economist at the Dutch University of Tilburg, attempted to determine the effects of a royal head of state on real GDP growth. Comparing World Bank data from constitutional monarchies with other forms of government, he concluded that, on average, the presence of a royal house accounts for 0.8 to 1.0 percentage points of additional economic growth. According to van Dalen, a ruler in a constitutional monarchy adds stability, efficiency, and social capital in the form of trust. In the case of the Netherlands, this "monarchy bonus" has added an estimated 4 to 5 billion euros to its 2006 GDP. Not a bad investment, considering the royal family's budget of roughly 100 million euros a year.

Dual-nation firms like Anglo-Dutch oil giant Royal Dutch Shell and Unilever have the option of traveling with two monarchs. However, the royal bump will only take you so far, says Wim van de Wiel, spokesman for Royal Dutch Shell. "In the end, it is still up to us to prove ourselves."

Just the same, monarchies do offer a competitive edge when it comes to international trade, especially with other kingdoms, says Herman Matthijs, political scientist and monarchy expert at the Belgian Universiteit Gent. "Royal visits to monarchies such as Thailand, the Gulf States, or Brunei bring in much more government contracts than those to countries like Vietnam or China. For instance, when the British government organizes a trade mission to the Persian Gulf, they send Prince Charles. He always comes back with enormous orders for the defense industry."

MORE: Have headquarters, will travel

As members of an exclusive club, royals feel connected to each other, even though differences between countries and political systems may be enormous. "Autocratic rulers may not like democracies," Matthijs says, "but they do look up to royal titles. If King Willem-Alexander decides to go to Riyadh, the Saudi King will want to see him that very night. He will probably pick him up from the airport personally. I don't see that happening to, say, the president of Italy."

This diplomatic equality allows small European monarchies to punch above their weight. Although nothing trumps a trade mission led by a U.S. president. "That opens all doors," says Matthijs.

Royal families also offer several branding lessons to businesses, says Harvard Business School marketing professor Stephen Greyser, who collaborated in a study of monarchies as corporate brands. "Monarchy is a symbol of nationhood and has a target market of a wide range of stakeholders. In that respect, they almost behave like corporations themselves."

Businesses can profit when a royal family endorses high-end domestic brands. "These forms of co-branding show that the monarchy is supporting national products competing in a global market," Greyser says.

Monarchies also inspire businesses to do good. "Members of the royal family are making countless appearances in support of various organizations, especially in the philanthropic realm," says Greyser. "Corporations engaging in charitable causes can certainly learn from that."

Companies that operate within monarchies can also be awarded royal designations, a remnant of Napoleon's reign over large swaths of Europe. This royal stamp of approval indicates that an enterprise is of impeccable integrity, has national importance, is a leader in its field, and has been around for at least a century. Such companies can also incorporate a crown in their logos.

MORE: Suspicious spending: $605K for coffee with Apple's CEO

While a royal designation is considered somewhat old-fashioned in Western Europe, the effect is still tangible in the Middle East, says Oostwegel of Royal Haskoning. After designing the Port of Duqm in Oman, the company is aiming at developing its airports as well. "In those cases, it certainly helps to have a reputation as a solid and reliable partner."

Source: http://management.fortune.cnn.com/2013/04/30/the-business-case-for-monarchies/

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Gunmen surround Libyan foreign ministry to push demands

TRIPOLI (Reuters) - Gunmen surrounded Libya's foreign ministry on Sunday, calling for a law banning officials who worked for deposed dictator Muammar Gaddafi from senior positions in the new administration.

At least 20 pick-up trucks loaded with anti-aircraft guns blocked the roads while men armed with AK-47 and sniper rifles directed the traffic away from the building, witnesses said.

As well as surrounding the Libyan Foreign Ministry, armed groups also tried unsuccessfully to storm the Ministry of Interior and the state news agency, the prime minister said.

"These attacks will never get us down and we will not surrender," Ali Zaidan told a news conference.

"Those who think the government is frustrated are wrong. We are very strong and determined."

Tension between the government and armed militias have been rising in recent weeks since a campaign was launched to dislodge the groups from their strongholds in the capital.

Since Gaddafi was toppled by Western-backed rebels in 2011, Libya has been awash with weapons and roving armed bands that are increasingly targeting state institutions.

Sunday's protest was to demand a law - which has already been proposed - be passed, banning Gaddafi-era officials from senior government positions. The law could force out several ministers as well as the congress leader, depending on the wording adopted.

"The Ministry of Foreign Affairs will remain closed until the political isolation law is implemented," the commander of the militia told Reuters.

The foreign ministry had been targeted because some officials employed there had worked for Gaddafi, he said.

Libya's legislature, the General National Congress, has previously been prevented from voting on the bill, when protesters barricaded assembly members inside a building for several hours in March demanding they adopt the law.

"The country will remain in crisis so long as these people are present," assembly member Tawfiq Al-Shehabi told Reuters.

On Tuesday, the French embassy in Tripoli was bombed, the first major attack on a foreign target since September's deadly assault on the U.S. diplomatic mission in Benghazi. The attack showed the government's grip on the capital may be slipping.

(Reporting by Ghaith Shennib and Jessica Donati; Editing by Robin Pomeroy)

Source: http://news.yahoo.com/gunmen-surround-libyan-foreign-ministry-push-demands-100133466.html

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Monday, April 29, 2013

HBT: Top LA prospect Puig busted for reckless driving

Kevin Baxter of the L.A. Times has the details:

Dodgers prospect Yasiel Puig was arrested by police in Chattanooga, Tenn., early Sunday and charged with speeding, reckless driving and driving without proof of insurance.

A spokesman for the Hamilton County jail confirmed that Puig was booked Sunday morning and released a short time later. He has a hearing scheduled for the afternoon of May 14 in Hamilton County court.

Puig, rated the #47 overall prospect by Baseball America going into the season, was hitting .333 with a 1.010 OPS in 52 plate appearances with Double-A Chattanooga. The Dodgers signed the 22-year-old Cuban on June 27 last year on a seven-year, $42 million contract. Puig seemed to be on the fast track to the Majors. His arrest this morning is his first bump in the road.

Source: http://hardballtalk.nbcsports.com/2013/04/28/dodgers-prospect-yasiel-puig-arrested-in-tennessee/related/

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Sunday, April 28, 2013

Tuesday, April 23, 2013

Scientist identifies protein molecule used to maintain adult stem cells in fruit flies

Apr. 22, 2013 ? Understanding exactly how stem cells form into specific organs and tissues is the holy grail of regenerative medicine. Now a UC Santa Barbara researcher has added to that body of knowledge by determining how stem cells produce different types of "daughter" cells in Drosophila (fruit flies). T

he findings appear today in the Proceedings of the National Academy of Sciences.

Denise Montell, Duggan Professor of Molecular, Cellular and Developmental Biology at UCSB, and colleagues studied the ovaries of fruit flies in order to see stem cells in their natural environment. Because these organisms are excellent models for understanding stem cell biology, researchers were able to shed light on the earliest stages of follicle cell differentiation, a previously poorly understood area of developmental biology. "It is clear that the fundamental principles that control cell behavior in simple animals are conserved and control the behavior of our cells as well," she said. "There is so much we can learn by studying simple organisms."

Using a nuclear protein expressed in follicle stem cells (FSCs), the researchers found that castor, which plays an important role in specifying which types of brain cells are produced during embryonic development, also helps maintain FSCs throughout the life of the animal. "Having identified this important protein molecule in fruit flies, we can test whether the human version of the protein is important for stem cells and their daughters as well," said Montell. "The more we know about the molecules that govern stem cell behavior, the closer we will get to controlling these cells."

Her research team placed the evolutionarily conserved castor (Cas) gene, which encodes a zinc finger protein, in a genetic circuit with two other evolutionarily conserved genes, hedgehog (Hh) and eyes absent (Eya), to determine the fates of specific cell progeny (daughters). What's more, they identified Cas as a critical, tissue-specific target of Hh signaling, which not only plays a key role in maintaining follicle stem cells but also assists in the diversification of their progeny.

The study also shows that complementary patterns of Cas and Eya reveal the gradual differentiation of polar and stalk precursor cells at the earliest stages of their development. In addition, it provides a marker for cell fates and insight into the molecular and cellular mechanisms by which FSC progeny diverge into distinct fates.

Follicle cells undergo a binary choice during early differentiation. Those that turn into specialized cells found at the poles of egg chambers go on to make two cell types: polar and stalk. The three genes, Cas, Eya and Hh, work in various combinations, sometimes repressively, to determine which types of cells are formed. Cas is required for polar and stalk cell fate specification, while Eya is a negative regulator of these cells' fate. Hh is necessary for Cas to be expressed, and Hh signaling is essential to repress Eya.

"If you just had one of these markers, it was hard to tell what's going on," explained Montell. "All the cells looked the same and you had no idea when or how the process occurred. But now we can actually see how the cells acquire different identities."

Hh also plays many roles in embryonic development, adult homeostasis, birth defects, and cancer. Hh antagonists are currently in clinical trials for the treatment of several types of cancer. However, Hh signaling is important in so many different cell types and tissues that systemic delivery of such inhibitors may cause serious side effects. Therefore identifying the essential, tissue-specific effectors of Hh has the potential to lead to the identification of more specific therapeutic targets.

Someday, targeted inhibition of Hh signaling may be effective in the treatment and prevention of many types of human cancers.

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The above story is reprinted from materials provided by University of California - Santa Barbara, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Yu-Chiuan Chang, Anna C.-C. Jang, Cheng-Han Lin, and Denise J. Montell. Castor is required for Hedgehog-dependent cell-fate specification and follicle stem cell maintenance in Drosophila oogenesis. PNAS, April 22, 2013 DOI: 10.1073/pnas.1300725110

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/3pFbpMK9yM4/130422154949.htm

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Thursday, April 18, 2013

Mary Roach Cruises the Alimentary Canal

Science Talk

Mary Roach talks about her new book Gulp: Adventures on the Alimentary Canal, which traces what she calls "the whole food chute"

More Science Talk

Mary Roach talks about her new book Gulp: Adventures on the Alimentary Canal, which traces what she calls "the whole food chute."?


Source: http://rss.sciam.com/click.phdo?i=a183a4b704c97ba6120ea7a297c38852

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The doctor won't see you now? Study: US facing a neurologist shortage

The doctor won't see you now? Study: US facing a neurologist shortage [ Back to EurekAlert! ] Public release date: 17-Apr-2013
[ | E-mail | Share Share ]

Contact: Rachel Seroka
rseroka@aan.com
612-928-6129
American Academy of Neurology

MINNEAPOLIS Americans with brain diseases such as Alzheimer's disease, Parkinson's disease or multiple sclerosis (MS) who need to see a neurologist may face longer wait times or have more difficulty finding a neurologist, according to a new study published in the April 17, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology. The findings are being released as nearly 150 neurologists will descend on Capitol Hill next Tuesday, April 23, 2013, to encourage Congress to protect patients' access to neurologists and ensure there will be care for the one in six Americans currently affected by brain disease.

"We want Congress to act now to help alleviate this shortage at a time when baby boomers are aging and the number of people with Alzheimer's disease is expected to triple by 2050," said Timothy A. Pedley, MD, FAAN, President of the American Academy of Neurology, the world's largest association of neurologists. "Neurologists are the physicians best suited to care for the one in six people currently affected by neurological disease. It is therefore vital that they have access to neurologists who are specially trained in treating brain diseases."

Cognitive care, or face-to-face time with neurologists, is undervalued by the current Medicare payment system and neurologists participating in next Tuesday's Neurology on the Hill will be asking for fair reimbursement for face-to-face care of neurology patients. Without fair and stable reimbursement, medical students and residents who have substantial education debt often are forced to seek more financially rewarding specialties than neurology.

"With the rapidly rising rates of brain diseases such as dementia and stroke at the same time as the number of US medical residents choosing neurology over other specialties is clearly declining, the US could face a crisis," said study author Thomas R. Vidic, MD, with Elkhart Clinic in Elkhart, Indiana and a Fellow with the American Academy of Neurology. "Our study found that long wait times for patients to see a neurologist and difficulty finding neurologists to fill vacant positions are adding to the current national shortfall. In addition, the demand for neurologists is expected to grow as people gain coverage through health care reform."

For the study, researchers created future year projections by reviewing the current number of US neurologists and simulating retirement probability, new graduates, and patient care hours worked.

The study found that the demand for neurologists will grow faster than the supply. The US could use 11 percent more neurologists to meet current needs. By 2025, that number will grow to 19 percent. The study found that the estimated 16,366 US neurologists is projected to increase to 18,060 by 2025, while demand for neurologists is projected to increase from about 18,180 in 2012 to 21,440 during that time.

Previous studies have shown that the average wait times to see a neurologist are increasing. The average wait time for a new patient to see a neurologist in 2012 was 35 business days, up from 28 business days in 2010. The average wait for a follow-up visit in 2012 was 30 days, up from 26 days in 2010. Other studies have shown that these wait times are longer than those for new visits for family practitioners, cardiologists and other specialties.

###

The study was supported by the American Academy of Neurology and an educational grant from Lilly, USA, LLC.

Since 2003, more than 600 members of the Academy have participated in Neurology on the Hill. View a list of neurologists participating in the 2013 Neurology on the Hill at http://www.aan.com/news/?event=read&article_id=11201. To learn more about brain disease, visit http://www.aan.com/patients.

The American Academy of Neurology, an association of more than 26,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer's disease, stroke, migraine, multiple sclerosis, brain injury, Parkinson's disease and epilepsy.

For more information about the American Academy of Neurology, visit http://www.aan.com or find us on Facebook, Twitter, Google+ and YouTube.

Editor's Note: The study includes information about the supply and demand for neurologists in each state.

Media Contacts: Rachel Seroka, rseroka@aan.com, (612) 928-6129
Michelle Uher, muher@aan.com, (612) 928-6120


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


The doctor won't see you now? Study: US facing a neurologist shortage [ Back to EurekAlert! ] Public release date: 17-Apr-2013
[ | E-mail | Share Share ]

Contact: Rachel Seroka
rseroka@aan.com
612-928-6129
American Academy of Neurology

MINNEAPOLIS Americans with brain diseases such as Alzheimer's disease, Parkinson's disease or multiple sclerosis (MS) who need to see a neurologist may face longer wait times or have more difficulty finding a neurologist, according to a new study published in the April 17, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology. The findings are being released as nearly 150 neurologists will descend on Capitol Hill next Tuesday, April 23, 2013, to encourage Congress to protect patients' access to neurologists and ensure there will be care for the one in six Americans currently affected by brain disease.

"We want Congress to act now to help alleviate this shortage at a time when baby boomers are aging and the number of people with Alzheimer's disease is expected to triple by 2050," said Timothy A. Pedley, MD, FAAN, President of the American Academy of Neurology, the world's largest association of neurologists. "Neurologists are the physicians best suited to care for the one in six people currently affected by neurological disease. It is therefore vital that they have access to neurologists who are specially trained in treating brain diseases."

Cognitive care, or face-to-face time with neurologists, is undervalued by the current Medicare payment system and neurologists participating in next Tuesday's Neurology on the Hill will be asking for fair reimbursement for face-to-face care of neurology patients. Without fair and stable reimbursement, medical students and residents who have substantial education debt often are forced to seek more financially rewarding specialties than neurology.

"With the rapidly rising rates of brain diseases such as dementia and stroke at the same time as the number of US medical residents choosing neurology over other specialties is clearly declining, the US could face a crisis," said study author Thomas R. Vidic, MD, with Elkhart Clinic in Elkhart, Indiana and a Fellow with the American Academy of Neurology. "Our study found that long wait times for patients to see a neurologist and difficulty finding neurologists to fill vacant positions are adding to the current national shortfall. In addition, the demand for neurologists is expected to grow as people gain coverage through health care reform."

For the study, researchers created future year projections by reviewing the current number of US neurologists and simulating retirement probability, new graduates, and patient care hours worked.

The study found that the demand for neurologists will grow faster than the supply. The US could use 11 percent more neurologists to meet current needs. By 2025, that number will grow to 19 percent. The study found that the estimated 16,366 US neurologists is projected to increase to 18,060 by 2025, while demand for neurologists is projected to increase from about 18,180 in 2012 to 21,440 during that time.

Previous studies have shown that the average wait times to see a neurologist are increasing. The average wait time for a new patient to see a neurologist in 2012 was 35 business days, up from 28 business days in 2010. The average wait for a follow-up visit in 2012 was 30 days, up from 26 days in 2010. Other studies have shown that these wait times are longer than those for new visits for family practitioners, cardiologists and other specialties.

###

The study was supported by the American Academy of Neurology and an educational grant from Lilly, USA, LLC.

Since 2003, more than 600 members of the Academy have participated in Neurology on the Hill. View a list of neurologists participating in the 2013 Neurology on the Hill at http://www.aan.com/news/?event=read&article_id=11201. To learn more about brain disease, visit http://www.aan.com/patients.

The American Academy of Neurology, an association of more than 26,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer's disease, stroke, migraine, multiple sclerosis, brain injury, Parkinson's disease and epilepsy.

For more information about the American Academy of Neurology, visit http://www.aan.com or find us on Facebook, Twitter, Google+ and YouTube.

Editor's Note: The study includes information about the supply and demand for neurologists in each state.

Media Contacts: Rachel Seroka, rseroka@aan.com, (612) 928-6129
Michelle Uher, muher@aan.com, (612) 928-6120


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-04/aaon-tdw041713.php

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Wednesday, April 17, 2013

Utility fights chronic disease with full-on wellness push ? Business ...

In 2005, Georgia Power discovered that more than 53% of its 8,500 em??ployees had or were at risk of developing a chronic health condition.

Since then, the Atlanta-based utility has enrolled thousands of employees in its ?Southern LifeStyle? wellness program, which has helped workers slim down, eat healthier and cut their risk for diseases.

Some of the program?s components include:

  • Lifestyle-changing programs that focus on tobacco cessation, stress management, weight management, diet, exercise and health screenings.
  • Health management programs that target diabetes, coronary disease, cancer, asthma, depression, obesity, hypertension and lower back pain.
  • Health education programming that teaches employees about disease prevention and how to be better consumers of health care.
  • Screenings, such as mammograms, tests for cardiovascular disease and skin cancer?all available in the company?s on-site medical clinics, where em??ployees can also get wellness phy?sicals.

Georgia Power also has a number of on-site fitness centers and reimburses employees who join outside gyms. Employees who participate in some of the programs earn a discount on their health insurance premiums.

Contact: Georgia Power, (404) 506-7676.

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Scientists discover new materials to capture methane

Apr. 16, 2013 ? Scientists at Lawrence Livermore National Laboratory (LLNL) and UC Berkeley and have discovered new materials to capture methane, the second highest concentration greenhouse gas emitted into the atmosphere.

Methane is a substantial driver of global climate change, contributing 30 percent of current net climate warming. Concern over methane is mounting, due to leaks associated with rapidly expanding unconventional oil and gas extraction, and the potential for large-scale release of methane from the Arctic as ice cover continues to melt and decayed material releases methane to the atmosphere. At the same time, methane is a growing source of energy, and aggressive methane mitigation is key to avoiding dangerous levels of global warming.

The research team, made up of Amitesh Maiti, Roger Aines and Josh Stolaroff of LLNL and Professor Berend Smit, researchers Jihan Kim and Li-Chiang Lin at UC Berkeley and Lawrence Berkeley National Lab, performed systematic computer simulation studies on the effectiveness of methane capture using two different materials -- liquid solvents and nanoporous zeolites (porous materials commonly used as commercial adsorbents).

While the liquid solvents were not effective for methane capture, a handful of zeolites had sufficient methane sorption to be technologically promising. The research appears in the April 16 edition of the journal, Nature Communications.

Unlike carbon dioxide, the largest emitted greenhouse gas, which can be captured both physically and chemically in a variety of solvents and porous solids, methane is completely non-polar and interacts very weakly with most materials.

"Methane capture poses a challenge that can only be addressed through extensive material screening and ingenious molecular-level designs," Maiti said.

Methane is far more potent as a greenhouse gas than CO2. Researchers have found that the release of as little as 1 percent of methane from the Arctic alone could have a warming effect approaching that being produced by all of the CO2 that has been pumped into the atmosphere by human activity since the start of the Industrial Revolution.

Methane is emitted at a wide range of concentrations from a variety of sources, including natural gas systems, livestock, landfills, coal mining, manure management, wastewater treatment, rice cultivation and a few combustion processes.

The team's research focused on two different applications -- concentrating a medium-purity methane stream to a high-purity range (greater than 90 percent), as involved in purifying a low-quality natural gas; and concentrating a dilute stream (about 1 percent or lower) to the medium-purity range (greater than 5 percent), above methane's flammability limit in air.

Through an extensive study, the team found that none of the common solvents (including ionic liquids) appears to possess enough affinity toward methane to be of practical use. However, a systematic screening of around 100,000 zeolite structures uncovered a few nanoporous candidates that appear technologically promising.

Zeolites are unique structures that can be used for many different types of gas separations and storage applications because of their diverse topology from various networks of the framework atoms. In the team's simulations, one specific zeolite, dubbed SBN, captured enough medium source methane to turn it to high purity methane, which in turn could be used to generate efficient electricity.

"We used free-energy profiling and geometric analysis in these candidate zeolites to understand how the distribution and connectivity of pore structures and binding sites can lead to enhanced sorption of methane while being competitive with CO2 sorption at the same time," Maiti said.

Other zeolites, named ZON and FER, were able to concentrate dilute methane streams into moderate concentrations that could be used to treat coal-mine ventilation air.

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Story Source:

The above story is reprinted from materials provided by DOE/Lawrence Livermore National Laboratory.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Jihan Kim, Amitesh Maiti, Li-Chiang Lin, Joshuah K. Stolaroff, Berend Smit, Roger D. Aines. New materials for methane capture from dilute and medium-concentration sources. Nature Communications, 2013; 4: 1694 DOI: 10.1038/ncomms2697

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_technology/~3/xCqiVccj4VA/130416132807.htm

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Tuesday, April 16, 2013

Discover the Text-Based Adventure Game Built Into Your Mac's Terminal

Everyone seems to love "retro" 8-bit video games, but it doesn't get much more retro than a text-based adventure. If you've never tried one before, or you're just bored and have a Mac nearby, open up Terminal and give its built in MUD (multi-user dungeon) text adventure a spin.

You won't need to download anything here, as the game runs within Emacs, a text editor that you can access through the Terminal. Just type the following into Terminal, and the game will launch automatically.

emacs -batch -l dunnet

If you've never played a MUD text adventure before, you'll find that it's actually pretty intuitive. For example, you start the game standing on a road with a shovel nearby. Type "take shovel" to add the shovel to your inventory, and "go east" to walk down the road. Typing "Inventory" will show you what you're carrying, "save" and "restore" let you play through in multiple sessions, and "help" gives you some tips if you're stuck. I'd also recommend using some scratch paper to map out the area as you discover it. Check out the source link for a few other Terminal easter eggs to help you kill some time this weekend.

Terminal 101: 4 emacs Easter eggs | Mac|Life

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/SobRdBHJZbk/discover-the-text+based-adventure-game-built-into-your-macs-terminal

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Biomarker for devastating intestinal disease, necrotizing enterocolitis, found in early preterm infants

Apr. 15, 2013 ? Researchers have discovered a biomarker that may help prevent a devastating intestinal disease that occurs in one of every 10 early preterm infants.

The Cincinnati Children's Hospital Medical Center study may help prevent necrotizing enterocolitis (NEC), a condition primarily seen in preemies in which bowel tissue dies. The death rate approaches 30 percent. Survivors are at risk for short-bowel syndrome (caused by surgical removal of the small intestine) and neurodevelopmental disability.

The study is published in the journal Microbiome.

The research, led by Ardythe Morrow, PhD, shows that NEC is preceded by two distinct microbial imbalances in the digestive tract, suggesting that these imbalances "may provide highly predictive biomarkers of NEC," she says.

"Using a combination of early microbial factors, we obtained a predictive value for NEC exceeding 80 percent," says Dr. Morrow. "This requires validation in larger studies, but the findings are striking."

Dr. Morrow's main analysis looked at stool and urine samples collected from 32 infants prior to the onset of disease. The infants were born at less than 29 weeks gestational age.

Eleven of the 32 went on to develop NEC. In all of these cases, NEC was preceded by a dominance of certain types of bacteria in the intestinal tract -- either firmicutes in the first week of life or proteobacteria in the second week. Dominance of proteobacteria also occurred in half of those who did not develop NEC.

The team of investigators led by Dr. Morrow also identified a potential simple urine analysis that could help detect the bacterial dominance that occurs in advance of NEC. The research team will attempt to validate its findings in a national study and is studying approaches to prevent the occurrence of NEC in preterm infants.

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Story Source:

The above story is reprinted from materials provided by Cincinnati Children's Hospital Medical Center.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Ardythe L Morrow, Anne J Lagomarcino, Kurt R Schibler, Diana H Taft, Zhuoteng Yu, Bo Wang, Mekibib Altaye, Michael Wagner, Dirk Gevers, Doyle V Ward, Michael A Kennedy, Curtis Huttenhower, David S Newburg. Early microbial and metabolomic signatures predict later onset of necrotizing enterocolitis in preterm infants. Microbiome, 2013; 1 (1): 13 DOI: 10.1186/2049-2618-1-13

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/O1rlLTzHcF8/130415204907.htm

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Monday, April 15, 2013

Frustration as retrial of Egypt's Mubarak aborted

By Yasmine Saleh and Maggie Fick

CAIRO (Reuters) - The retrial of former Egyptian President Hosni Mubarak was aborted on Saturday when the presiding judge withdrew from the case and referred it to another court, causing an indefinite delay that sparked anger in the courtroom.

Lawyers said that while the transfer would give prosecutors more time to draw on new evidence in an unpublished fact-finding commission's report into the repression, it could delay the case by months, increasing the risk that Mubarak, 84, may never be finally convicted and sentenced.

"Egypt cannot close the door on the former regime until there is justice for the martyrs of our revolution," said Mohamed Rashwan, a prosecution attorney and member of the Egyptian Lawyers' Union, which had petitioned to have the judge removed from the case. Two years had passed since Mubarak's fall and justice was taking too long, Rashwan said.

"The people demand the execution of Mubarak!" frustrated relatives of demonstrators killed in the 2011 uprising that overthrew him chanted in court after presiding Judge Mustafa Hassan Abdullah announced the decision at the opening session.

Outside the heavily guarded compound, pro-Mubarak demonstrators outnumbered opponents. The two small groups were kept well apart by a police cordon and there were no incidents.

Mubarak, who ruled Egypt for almost 30 years before being toppled by 18 days of Arab Spring pro-democracy unrest, waved and smiled to supporters from the defendants' cage in the courtroom before the brief hearing began.

He was flown by helicopter from a military hospital where he has been detained to the police academy used as a courthouse, and wheeled from an ambulance into the building lying on a hospital trolley wearing a white tracksuit.

Mubarak, former interior minister Habib al-Adli and four top aides face a retrial for complicity in the murder of more than 800 protesters after the highest appeals court accepted appeals by both the defense and the prosecution in January. Two other senior interior ministry officials face lesser charges.

The presiding judge was appointed under Mubarak and so were most of the current judiciary, a factor that has complicated transitional justice in Egypt. The judge said he had decided to refer the case to the Cairo appeals court as he felt "unease" in reviewing the case. He did not explain his decision further.

He had previously acquitted top former Mubarak era officials of orchestrating violence when thugs riding camels attacked pro-democracy activists in Cairo's central Tahrir Square.

"We ask for the harshest possible sentence on Mubarak due to the cruel crimes he committed against the protesters, but we are happy with the judge's decision to withdraw as we had worries about him given his ruling (on) the camel attack case," said Mohamed Abdel Wahab, a lawyer for the victims. His comment reflected a widespread mixture of relief and frustration.

COMPETING DEMONSTRATIONS

It was the first time Mubarak, who wore gold-rimmed aviator sunglasses in court, had been seen in public since he and Adli were convicted last June on grounds of failing to stop the killing, rather than actually ordering it.

Mubarak's two sons, Alaa and Gamal, were also in court to be retried on separate charges of financial corruption.

Propped up on a gurney in a cage with the other defendants, he looked fitter and more relaxed than on previous appearances in the dock, holding animated conversations with his son Gamal, and occasionally smiling and waving to people in the courtroom.

Judge Mahmoud el-Hafnawy of the prosecutor general's office ordered an urgent medical report on the former president to determine whether he was now fit enough to be sent to prison.

Prosecutors accuse Mubarak of giving orders to Adli to open fire with live ammunition against protesters to suppress demonstrations across the Arab world's most populous country.

Mubarak and his interior minister were sentenced to life imprisonment at their first trial but the appeals court upheld complaints stemming from the weakness of the evidence offered by the prosecution.

Outside the court, pro-Mubarak demonstrators chanted "thirty years without destruction!" in reference to accusations that the Muslim Brotherhood movement which won free elections after his ouster are destroying the country.

"Look at the country now," said a supporter who gave his name as Ibrahim. "We are going bankrupt. The whole country is suffering from this economic crisis, from this lack of security."

Across the square, relatives of victims of Mubarak's security forces held posters of young men killed in the revolt.

Mahmoud Saleh, whose son Mostafa was killed during revolution, said: "He who kills must be killed. This is what we want from the trial."

Mubarak became the first ruler toppled by the Arab Spring uprisings to stand trial in person. That irked Gulf Arab rulers in Saudi Arabia and the United Arab Emirates, of whom the former air force commander had been a loyal ally for decades.

But the case has also exposed the difficulties of justice in a country where the judiciary and security forces are still largely run by men whose positions date to the Mubarak era.

The prosecution complained that the interior ministry had failed to cooperate in providing evidence, leading to the acquittal of six senior ministry officials tried with Mubarak.

Mohamed Gomaa, 50, an IT specialist whose son Hussein, 23, was killed in the uprising, said: "Major reforms are needed in the entire justice system. Until then, we can only hope to God for a fair trial for Mubarak. I have no confidence in the judiciary."

(Additional reporting by Tom Perry; Writing by Paul Taylor; Editing by Mark Heinrich)

Source: http://news.yahoo.com/egypts-mubarak-flown-court-retrial-tv-070906417.html

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Sunday, April 14, 2013

Which Celebrities Have the Most Fake Twitter Followers?

Did you hear? Nearly half of Justin Bieber's Twitter followers are fake. Fake! Belieber nation is a fraud, life has no meaning, the abyss of treachery and betrayal that is life grows deeper by the hour. More »
    


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/W66Ggf5gHvQ/which-celebrities-have-the-most-fake-twitter-followers

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As Berlin Awaits Its Big Tech Exit, Satirical Tumblr Blogs Spawn About The Hype

Screen Shot 2013-04-14 at 15.17.20The hype about the Berlin tech startup scene has continued this year, but as 2013 ebbs into spring, many are asking the same question: When will the hype turn into real results? As many of my contacts said to me on a recent visit: what we need in Berlin for all this hype to be real is a big exit. The most recent evidence that Berlin is capable of producing a decent startup exit is the sale of streaming music tech company Aupeo to Panasonic Automotive, although the financial terms remain a mystery.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/geRCPW0BLH8/

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Social media interactions could hurt marriage - London Free Press

Oh, sure, you think it's cute now to tweet each other or post on one another's Facebook walls, but too much Internet intercourse could hurt a marriage in the long run.

The theory of "media multiplexity" says there is a link between the number of media channels we use to communicate, how often we use them and the strength of our relationships ? and that was developed when all we had was e-mail, instant message and telephone.

Researchers at the Internet Institute at the University of Oxford, in England, conducted a new study involving 24,000 married people and 10 media channels, and found that some of the couples reported decreased satisfaction with their relationship.

The findings, they said, suggest there may be a cut-off point where relationships start to weaken because of the difficulty maintaining the many communication threads in use today.

The study was presented at the Annual Conference of the British Psychological Society.

?

Source: http://www.lfpress.com/2013/04/12/couples-social-media-interactions-could-hurt-marriage-study

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In the virtual cockpit: What it takes to fly a drone

Drone pilots escape the physical demands and dangers of a traditional cockpit. There's no g-force pinning them to their seats, no uncomfortable pressure suit to wear and no panic because the aircraft they are sitting in is spiraling out of control.

Instead of soaking in sensory information through their eyes and ears and fingers, drone pilots spend hours watching their crafts through their computer screens ? their only physical link with the craft they fly.

Over the last few years, the military has been taking on drones faster than it can train pilots. The old guard, airmen and women who clocked flight hours in regular aircraft before taking control of a Predator, is being replaced by a generation of cadets with basic flight training and hours and hours of video game time. Drones themselves are evolving into complex automatons, making novel demands on their minders' brains and bodies. Scientists who study how machines and humans work together are only just filling in our understanding of what it really means to be a drone pilot.

A drone operator who has a flying history will tell you that switching gears to remote control takes some getting used to.

In a manned aircraft, "you can see outside, where you can hear the noise of the engine and hear the turbulence ? You have all your five senses," Phil Hall, a pilot for NASA's Global Hawk research drone, told NBC News.

But drone pilots today rely on a computer screen, system status updates and a map, sometimes continents away from the craft they are flying.

"In a manned aircraft if you have a problem you know right away," Hall said, but when there's a drone involved, there's a bit of translation, and there's only so much of the situation you can read.

Some of the hardest lessons to teach new drone pilots? Where to look for information that in a manned craft would be right at their fingertips, says Tom Miller, an ex-Air Force pilot who now flies NASA's Global Hawk drone. For example, in the case of a lost data link, a drone is programmed to return to either a pre-programmed location or its original launch point. When that happens, "A pilot needs to know what the programming is if they need to manage it," so the programming can be changed if needed, Miller said.

Boredom an issue
Drones like the Global Hawks are so sophisticated that they need more minding than flying. In other words, flying a drone doesn't suck up every drop of a pilot's focus every second they are at the controls. This makes boredom a unique but very real problem among pilots, and it cuts into their performance, a study published last year found.

Missy Cummings, an ex-Navy pilot and MIT professor who led the study, explained that "babysitting" a craft while waiting for a target makes it harder for pilots to spring back into action when they're needed. When she tested the subjects' attention through 4-hour simulations, she found that high scorers were distracted: They read a book, checked their phones or left the controls to get a snack.

But training for one drone doesn't mean you're ready to fly another, as drone controls can vary greatly between models. "They're apples and oranges," Hernan Posada, who pilots NASA's Predator named Ikhana, said. Predator drones, among the oldest, are operated with a stick and rudder, while the newer Global Hawk is controlled with a mouse and keyboard. The Predator is less autonomous and needs a lot more manual control, especially during take offs and landings, Posada explained.

"A lot" of unmanned aircraft systems were "built as if a (jet) pilot was going to fly it," which explains the rudder and stick, Raza Waraich who has studied the link between control design and rates of crashes, said. But newer designs are made for those without flight training to fly the craft. "I found a couple of UAVs (Unmanned Aerial Vehicles) that incorporate the PlayStation2 controller," he said, explaining that pilots would use the video game controller to navigate menus.

Which is just as well, since some believe the newest recruits into drone flight school are already wired differently. "They grow up playing Xbox and Nintendo and gaming systems ... they have a different multitasking capability, they collaborate differently with their fellow pilots" and other operators, said Brad Hoagland, a colonel with 23 years in the Air Force, who is now studying drones and drone pilots as a Federal Executive Fellow at the Brookings Institution.

Different physical cues
Starting in 2010, the Air Force designated drone piloting as its own career path. Trainees would complete one tough year without going through undergraduate pilot training, motivated in part because the Air Force's targeted need for operators was higher than the rate at which they are graduating.

"We've been building the platform faster than we can fill them with operators," Hoagland said.

There's some evidence that suggests putting a pilot with less flight experience behind the drone controls is a better strategy than the other way around.

"Pilots in an aircraft are used to an entirely different set of physical cues," MIT's Cummings said in an email. A 2004 report that studied drone accidents showed that pilots with real flight experience made more mistakes than operators with no flight experience. That's because "pilots learn to rely on a set of cues they do not have in the control of UAVs so it is not clear that pilots are the best qualified people for control of drones," Cummings said.

But pilots who made the switch seem happy with their decision. Hoagland, citing an internal Air Force study, said 487 fighter and bomber pilots were assigned to a three-year stint on drone duty, and when their time was up, 412 of those mid- to late-career pilots decided to stick with drones. The younger cadets have caught the bug too, he says. When a brood of 244 fresh undergraduates were given a chance to pick any career in the Air Force, 25 percent of them decided to become drone pilots.

Nidhi Subbaraman writes about technology and science. Follow her on Twitter and Google+.

Source: http://feeds.nbcnews.com/c/35002/f/653381/s/2aabcd0e/l/0L0Snbcnews0N0Ctechnology0Ctechnolog0Cvirtual0Ecockpit0Ewhat0Eit0Etakes0Efly0Edrone0E1C9319684/story01.htm

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Saturday, April 13, 2013

Senators get deal on farm worker wages in immigration bill

By Richard Cowan and Charles Abbott

WASHINGTON (Reuters) - Senators negotiating an immigration bill have reached agreement on wages for foreign farm laborers working in the United States and a limit on visas for such workers, Democratic Senator Dianne Feinstein said on Thursday.

Feinstein, of California, refused to provide details on the agreement and added that there were some other issues related to farm workers still to be negotiated.

"We have an agreement on wages and the visa cap," Feinstein told Reuters. The deal followed a six-hour negotiating session on Wednesday, she said.

The farm worker portion of the bill is seen as the last major bit to be negotiated before Senate legislation is introduced in coming days.

The government estimates that of the 1.1 million workers in agriculture, at least half are undocumented.

An immigration bill, which will attempt a comprehensive update of U.S. policy for the first time since 1986, will try to end years of illegal hiring of foreign workers amid labor shortages in some sectors. It also will aim to put many of the estimated 11 million people living in the United States illegally - some for decades - on a path to citizenship.

Craig Regelbrugge, a member of an agricultural employer coalition, said "there are still important issues unresolved."

A key issue is the legal status for the tens of thousands of farm workers who entered the United States without documents.

The United Farm Workers union argues they should be given permanent resident status and the opportunity for citizenship. The Agriculture Workforce Coalition, representing employers, has suggested that legalization be tied to a commitment to work in agriculture for a specified number of months.

'NEVER MORE OPTIMISTIC'

Farm labor reform has two major parts - a decision on how to treat workers in the country illegally and revamping of the guest worker program. Employers want a new program to replace the H-2A program, which they say makes it difficult to recruit enough workers in a timely manner and sets wages too high. The union has warned against formulas that would depress wages.

The Senate Judiciary Committee has scheduled a hearing for Wednesday on the comprehensive immigration bill that a group of eight Democratic and Republican senators has been negotiating for months.

While Feinstein is not a member of that group, she has been a lead negotiator on the farm worker portion of the bill, which is very important to California, the nation's largest agricultural producing state.

Republican Senator John McCain of Arizona, a leading member of the group of eight senators negotiating the bill, told reporters that it was now "time to get it finished and introduced."

When asked when the bill would be unveiled, he said it would happen very soon.

Another Republican senator in the "gang of eight," Lindsey Graham of South Carolina, said he had "never felt more optimistic" about an immigration bill moving forward in the Senate.

But he said, "You always worry that something this complicated and emotional won't make it through."

Graham added, "The key is keeping business and labor (unions) together on the guest worker program" that aims to accommodate immigrant workers in agriculture and low-skilled construction workers, hotel maids and restaurant employees.

(Additional reporting by Rachelle Younglai; Editing by Will Dunham and Eric Walsh)

Source: http://news.yahoo.com/senate-immigration-plan-creates-complex-road-citizenship-003217897.html

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Friday, April 12, 2013

National Partnership for Women and Families: National Partnership ...

FOR IMMEDIATE RELEASE


Written Statement of Judith L. Lichtman, Senior Advisor, National Partnership for Women & Families. Submitted to the U.S. House Committee on Education and the Workforce Subcommittee on Workforce Protections Hearing on H.R. 1406, the Working Families Flexibility Act.

WASHINGTON, D.C. ? April 11, 2013 ? Good morning, Chairman Walberg, Ranking Member Courtney, members of the Committee and my fellow panelists. I appreciate the opportunity to testify before you today on H.R. 1406.

I am Judith Lichtman, senior advisor at the National Partnership for Women & Families, a nonprofit, nonpartisan advocacy organization. For four decades, we have fought for every major policy advance that has helped women and families. We promote fairness in the workplace, access to quality, affordable health care, and policies that help women and men meet the dual demands of work and family. Our goal is to create a society that is free, fair and just, where nobody has to experience discrimination, all workplaces are family friendly, and every family has access to quality, affordable health care and real economic security.

Formerly the Women?s Legal Defense Fund, the National Partnership for Women & Families is proud to have drafted the Family and Medical Leave Act (FMLA) and led the coalition that fought to make it law. Since 1993, women and men have used the FMLA more than 100 million times to care for themselves or their loved ones. It is an historic law that has had a tremendous impact, and a shining example of what can be accomplished when lawmakers work together to address the nation?s needs. The FMLA was intended as a first step toward a nation with public policies that truly value families.

It Is Time to Update Our Nation?s Family Friendly Laws, But H.R. 1406 Offers a False Choice Between Time and Pay

As lawmakers on both sides of the aisle have acknowledged, people today are struggling to meet the demands of job and family, as well as to make ends meet. In most families, all adults work. Women comprise half of the workforce and women?s earnings are essential to their families. Women also remain primary caregivers in most families.

We all know these are tough times. Across the nation, women and men are struggling to get by on less, and to meet both the demands of their employers and the needs of their families. They are worrying about whether their jobs are secure, and trying to hold onto them without the time off they need. Many also contend with work schedules that are unpredictable, inflexible and unstable.

So it should be no surprise that, in a survey commissioned by the National Partnership in November 2012, 80 percent of working women and 72 percent of working men said they, their neighbors or their friends face hardships when managing work, family and personal responsibilities.

There is no question that Americans need lawmakers to take the next step on the road to a family friendly nation. But H.R. 1406 is not what the nation needs. It is, at best, an empty promise. In truth, it would cause considerably more harm than good.

Quite simply, H.R. 1406 would be a step in the wrong direction. Instead of building on the success of policies such as the FMLA, paid sick days standards and a fair minimum wage which provide workers and their families with the time off and the financial stability they need this ?flexibility? bill offers forced choices and false promises.

This legislation is based on smoke and mirrors. It pretends to offer the time off people need when they need it, but in fact, it is a pay cut for workers without any attendant guarantee of time. It also sets up a dangerous, false dichotomy between time and money when, in fact, working families need both.

H.R. 1406 has been introduced multiple times, in identical form, since the late 1990s. Fortunately for the nation?s workers, it has not become law. That is good news because this bill would undermine the very purposes of the Fair Labor Standards Act (FLSA), which for 75 years has helped protect the working hours and paychecks of covered employees. The FLSA?s requirement that hourly, non-exempt employees be paid time-and-a-half for every hour of work in excess of 40 hours per week was intended to spread job opportunities to more workers and create disincentives for overwork, giving working women and men the ability to spend time with their loved ones.

H.R. 1406 would leave workers with neither pay nor time. Let me tell you about a woman the National Partnership and our colleague organization, Family Values @ Work, met in 2011 when we convened discussion groups to examine the challenges facing workers to inform the U.S. Department of Labor?s National Dialogue on Workplace Flexibility.

In Los Angeles, we met a widowed clerical aide we?ll call Susannah who has a 20-year-old son, a 19-year-old daughter, a 5-year-old daughter, and a 73-year-old mother with health problems. This hourly worker said her hours had been cut from 40 per week to 30, but her workload had not decreased. ?We put in a lot of ?voluntary? time,? she explained. ?We get told things like, ?If you can?t handle it or it?s too much work for you, maybe we can find someone else.?? Despite family obligations that required her to be home in the evenings, Susannah felt constant pressure from her supervisor to work extra hours on short notice. ?If I need to work overtime, I do it to keep my job,? she explained, even though those extra hours often created child- or elder-care problems and extra expenses. At the same time, Susannah said her employer treated her with suspicion when she needed to take a day off to care for her sick child. She said she sometimes goes to work sick for fear that taking a day off would mean losing her job.

Susannah is just one of the many workers whose experiences put a face on data from the Bureau of Labor Statistics and major national surveys that show declines in the value of workers? wages, declines in workers? control over their work hours and schedules, and growing fears of termination that prevent workers from asserting their rights. It also illustrates the family demands that workers face, and how hard it can be to care for children and parents at the same time, especially without guaranteed time off and enough income to cover unexpected expenses.

We heard from workers with similar stories all over the country, and their experiences shine a bright light on why H.R. 1406 is so deeply flawed. It would give workers less control over both their time and their paychecks. It does not guarantee the time off that workers need, regardless of their opportunity or ability to work overtime hours. And for the growing segment of workers whose challenges stem from the opposite problem working too few hours involuntarily with too little predictability this proposal would do absolutely nothing to assure access to either the pay or the paid time off they need to meet their family responsibilities.

Comp time, accepted freely and fairly and available on demand for non-vulnerable workers, may have a place in a suite of policy solutions to help workers and families. But H.R. 1406?s brand of comp time is designed to benefit employers only. It does not offer any of the protections workers need. It is tone-deaf to what workers are experiencing right now.

The following are our specific concerns about H.R. 1406.

H.R. 1406 Magnifies the Power Imbalance between Employees and Employers

H.R. 1406 places significant power in the hands of employers, while limiting the ability of employees to earn the wages they need to support their families. It permits employers to offer comp time in lieu of overtime to one, some or all eligible workers. And although it requires an ?agreement? between employers and employees, it does not give an employee wishing to remain in her or his employer?s good graces any true ?choice.? As a worker said recently in a focus group commissioned by the National Council of La Raza, ?[T]he employer can abuse you, can use you because you?re scared to lose your job. You lose your job, they fire you, they?ll get somebody else or two other people.?

Few hourly workers and almost none without union representation have real bargaining power in the workplace. These low-wage workers tend to rely on overtime pay to make ends meet. They also are at high risk for wage theft, where wages are withheld or reduced by unscrupulous or thinly capitalized employers.

In the current climate, in which Americans are deeply concerned about losing jobs or being unable to work enough hours to make ends meet, employees will be coerced into accepting comp time instead of pay, for fear of losing their livelihoods altogether. And, as I?ll discuss in a moment, the comp time offered here may not even be available when workers need it, rendering this proposal a true wolf in sheep?s clothing.

This legislation would put workers at very real risk. An employee who does not accept comp time could find himself or herself penalized with fewer hours, non-preferred shifts and loss of overtime work. The employee?s ?choice,? then, would be to accept comp time instead of needed pay or, if he or she reasonably asks for pay for overtime work and faces retaliation, try to fight it in court. That is an unrealistic expectation for workers who fear losing their jobs and have no resources with which to litigate.

H.R. 1406 Would Mean Less Work for Some and More Work and Extra Expenses for Others

H.R. 1406 undermines the central tenets of Section 7 of the FLSA: creating reasonable work hours for all, and work and job opportunities for many. Because it is cheaper for employers to provide comp time than to pay overtime wages, there is a significant incentive for employers to hire fewer people and rely on overtime hours paid for in future comp time to get work done. H.R. 1406 could translate into fewer jobs at a time when the economy needs more people working. And it would mean greater scheduling instability, uncertainty and unpredictability for workers who are asked to work overtime hours; potentially greater childcare and transportation expenses; and yet fewer dollars in workers? pockets to meet the additional costs and inconveniences that more overtime work would bring.

H.R. 1406 Means Less Paycheck Security for Employees and an Interest-Free Loan for Employers

H.R. 1406 would permit employers to defer compensation in money or time to employees for as many as 13 months. In essence, comp time creates an interest-free loan for employers because employees who work overtime today may not see the value of that overtime for more than a year.

The legislation allows employers to retain and earn interest on the wages they would otherwise have been obligated to pay. Although it is true that an employee can trade banked comp time for overtime pay, employers have a full 30 days to grant the request. That means that an employee who needs the overtime pay to make ends meet may have to wait a full month for it.

H.R. 1406 Fails to Provide the Time that Working People Need

The worker flexibility offered by H.R. 1406 is nothing more than a mirage. That?s because this proposal gives the employer, not the employee, the ?flexibility? to decide when and even if comp time can be used. The plain language of the bill requires an employee to make a request in advance, gives the employer a ?reasonable period? after the request is made to allow the employee to use the time, and permits the employer to deny the request entirely if the employee?s use of comp time would ?unduly disrupt? operations.

This means that a mother who asks to take comp time to stay home with her toddler because her child care provider is sick has no guarantee that she?ll be able to use the time she?s earned and banked. And there is no guarantee that a son?s request to use a week of comp time to help his aging parent relocate to a nursing home will be granted. Just as workers like Rosa, a hotel housekeeper, are denied the use of vacation leave they have earned for important family events like a daughter?s communion, so too will workers be denied the use of the comp time they have earned through long hours on the job.

If an employee?s request is arbitrarily or unfairly delayed or denied, H.R. 1406 provides no recourse. There is no remedy under this proposal for an employee who is unable to use accrued comp time, except to ask that the time be cashed out. This is far from the kind of family friendly policies workers need.

H.R. 1406 Jeopardizes Employees? Wages When Firms Die

All of this assumes the employer remains in business and employees can eventually use the time they?ve banked, or receive the cash equivalent when banked time is paid out. But H.R. 1406 provides no protections to employees when firms collapse or go bankrupt. As a result, a worker could lose the value of unused comp time up to 160 hours per employee, or more than $2,200 for a typical worker. The receipt of comp time in lieu of overtime could also have repercussions for employees seeking unemployment compensation.

This significant loss of income would affect not just individual employees but when large employers close their doors whole communities. On average, more than three million employees lose their jobs each year when businesses close. Even at the peak of the last business cycle, about 600,000 firms employing 3.4 million workers went out of business in one year. And during the most recent recession, firm deaths outnumbered firm births across all sectors.

H.R. 1406 Fails to Provide Affordable Remedies to Workers or Resources to the Department of Labor

Even under current wage and overtime law, unscrupulous employers regularly violate employees? rights to earn overtime payments because the benefits of non-compliance outweigh the financial liabilities. H.R. 1406 would increase employers? incentives to ignore the FLSA?s wage and overtime provisions. It does not provide administrative remedies for employees who have been coerced into accepting comp time or whose rights to freely choose comp time versus overtime payments have been violated. Instead, employees? only recourse is through the courts. But few low-wage workers have the resources to sue. And, as noted above, employees have no right at all to use the comp time they have accrued when they need it.

In addition, H.R. 1406 adds significant new provisions to the FLSA and creates a new imperative for employee and employer outreach, but provides no additional funds for the education and enforcement efforts its new provisions will require. The U.S. Department of Labor?s Wage and Hour Division already struggles to enforce the FLSA with too few investigators and too small a budget; recent fiscal pressures will only stretch DOL?s resources even more.

For each of these reasons and because employees simply should not have to put in extra time beyond a 40-hour week and forgo pay simply to earn time to care for themselves or their loved ones we ask you to reject H.R. 1406. It is a deeply flawed proposal that would cause massive harm to workers. It offers a false, flawed choice that would make times even tougher for workers and their families. It would be a giant step in the wrong direction for the country. We can do better.

Toward a More Family Friendly and Prosperous Nation: Public Policy Solutions That Workers and Families Need Most

We commend the committee for recognizing the important role that public policies can play in setting our nation?s course. Too often, work-family conflicts are seen as individual struggles to be managed privately rather than as a common thread that connects virtually every working parent or adult child and that binds the interests of employees, employers and communities.

False Assumptions Have Impeded Our Progress

For too long, a number of false assumptions have stood in the way of progress. The organized business lobby and other opponents have perpetuated the idea that family friendly policies are zero-sum, expensive and marginal to working families? economic stability and well-being. The opposite is true. Employees, families, businesses, taxpayers and government all have a stake in creating more family friendly workplaces and increasing the economic security of working families. I want to refute these false assumptions so we can move beyond them and consider the policy solutions working people need.

The most egregious myth perpetuated by the organized business lobby is that expanding work-family policies harms employers. Done right, these policies can benefit business. Research confirms what working families and responsible employers already know: When businesses take care of their workers, they are better able to retain them. Workers paid fair wages have more ability to support local businesses. And workers with the security of paid time off and flexibility increase their commitment, productivity and morale and employers reap the benefits of lower turnover and reduced training costs.

Studies show that the costs of losing an employee, including advertising for, interviewing and training a replacement, are often much greater than the cost of providing short-term leave to retain an existing worker. The average cost of turnover can range from 25 percent to 200 percent of an employee?s annual compensation. This is why the Council of Economic Advisors in 2010 recognized the imperative for more flexible, family friendly workplaces. And this is why a growing number of businesses are supporting increases in the minimum wage and the establishment of paid sick days and paid family leave laws.

A second, related myth is that humane leave policies are too costly for taxpayers. In reality, these policies provide cost-savings to governments as well as businesses. A recent study shows that if all workers had paid sick days, 1.3 million emergency room visits could be prevented each year in the United States, saving $1.1 billion annually. More than half of these savings $517 million would accrue to taxpayer-funded health insurance programs such as Medicare and the State Children?s Health Insurance Program. In addition, both women and men who take paid leave after a child?s birth are significantly less likely to rely on public assistance or food stamps in the following year. And women who take paid leave are more likely to be working nine to 12 months after a child?s birth and to have higher earnings. Like other policies that promote higher wages and economic opportunity, paid leave helps grow the economy and the tax base while reducing reliance on public services.

A third myth is that only women care about family friendly policies, which are marginal to families? economic security. Women remain our families? primary caregivers to children and elders. However, women are nearly half the workforce, men increasingly manage responsibilities at home as well as in the workplace, and both genders feel intense work-family conflict and need better ways to manage job and family responsibilities. Regardless of the gender of family caregivers, the absence of family friendly policies harms families financially.

It is time to reject these absurd myths, which have been disproven time and again, and instead work together to adopt innovations that are long overdue. We do not need to require workers to subsidize their own time off with lower wages and more time on the job, as H.R.1406 does. Instead, we need to adopt national policy solutions patterned on those working well in states and cities across the country. Paid sick days and paid family and medical leave would boost incomes and the economy and would, in many cases, lead to cost-savings over time for employers.

The policies I?ll discuss have strong popular support across the political spectrum. In a poll commissioned by the National Partnership last November, 86 percent of voters said it is important for Congress and the President to consider new laws to help keep working families economically secure, including ensuring workers the right to earn paid sick days and creating a system of paid family and medical leave insurance. Policies that would provide wage protections in the form of a higher minimum wage and fair pay for women have nearly universal support. Policies that would promote more flexibility and predictability for workers while recognizing the needs of business are overwhelmingly popular as well.

Families, Businesses and the Economy Will Benefit When Workers Are Paid Fair Wages

It is a huge problem for our country that the value of workers? wages has declined. That makes overtime pay even more important for workers who are able to work overtime. While H.R. 1406 would literally take money out of workers? paychecks, an increase in the minimum wage would promote greater financial stability.

The Fair Minimum Wage Act (H.R. 1010/ S. 460) would increase wages for 30 million workers, most of them women. Nearly 28 percent of those who would see a wage increase are parents; more than 17 million children have a parent who would benefit. A rise in the minimum wage would increase consumer spending, stimulating the economy. By the third year, when the minimum wage reaches $10.10 per hour, the Fair Minimum Wage Act would generate more than $32 billion in additional economic activity and approximately 140,000 jobs.

It is also a huge problem for the country that the gender-based wage gap is pervasive and unrelenting. Families headed by women pay an especially high price. Over the course of a year, wages paid to women with full-time, year round jobs average $11,000 less than the wages paid to men with full-time, year round jobs. That money could buy 89 weeks of food or pay more than a year of rent. The disparity for African American women and Latinas is even greater than for white women.

For many women who experience gender discrimination in wages, and whose families suffer as a result, overtime pay is key to financial stability. H.R. 1406 would further diminish their earnings by threatening these women?s ability to earn overtime pay.

In contrast, the Paycheck Fairness Act (H.R. 377/S. 84) would increase women?s financial stability by promoting fair pay practices. It would help women challenge and eliminate discriminatory pay practices, help train women and girls in salary negotiation, support government collection of critical wage data, and reward employers that have good pay practices. If you want to help women and their families and level the playing field, you will pass the Paycheck Fairness Act.

Employees Must be Able to Earn Paid Sick Days to Protect Their Health and Economic Security

Everyone gets sick or needs medical care, for themselves or their families, at some point. While H.R. 1406 does nothing to assure that workers will have sick days when they need them, the Healthy Families Act (H.R. 1286/S. 631) would allow 90 percent of the private sector workforce to earn paid sick time to use when they need it. The Healthy Families Act would ensure that most of the 43 million workers who do not have any paid sick time could start to accrue it. It would allow workers to earn up to seven paid sick days annually to use to recover from short-term illness, care for a sick family member, seek routine medical care or obtain assistance related to domestic violence, sexual assault or stalking. Employers that already provide this type of leave would not have to provide additional sick time, and small businesses with fewer than 15 employees would be exempt.

Families suffer when workers cannot earn paid sick time. For the average family without paid sick days, just a few days of lost income due to illness can jeopardize the families? grocery budget for an entire month. Nearly one in four adults nationwide has lost a job or been threatened with job loss for needing time away from work to address a personal or family illness.

The Healthy Families Act is a much more effective solution than H.R. 1406 in providing workers with the time they need to care for their loved ones and themselves. It guarantees employees the ability to use that time off while respecting employers? needs for stability in their business operations. For restaurant workers who cook our food, childcare workers who tend to our children and care workers who support the frail elderly, the Healthy Families Act would be a step forward while H.R. 1406 would be a step in the wrong direction. At a time when more than half of parents do not have even a few paid sick days they can use to care for an ill child and tens of millions of workers have family eldercare responsibilities, we need the real solutions the Healthy Families Act would provide.

Paid sick days laws are working well around the country. San Francisco, Washington, D.C., and Seattle have successfully implemented paid sick days standards, as has Connecticut. Portland, Oregon, and New York City will have paid sick days standards in place next year. San Francisco?s paid sick days law has been in place since 2007 and the number of businesses and jobs in the city has increased relative to the surrounding five counties. Workers and their families have benefitted with little to no burden on employers. In fact, two-thirds of San Francisco employers now support the city?s paid sick days law.

But illness knows no geographic boundaries. Access to paid sick days should not depend on your zip code. We need a national standard. A working mother in Alabama and a working father in Virginia should have the same right as workers in Connecticut to take a day away from work to care for a feverish child, a parent with a broken hip, or to get medical care. The Healthy Families Act would guarantee that time. H.R. 1406 would not.

Workers Need Paid Family and Medical Leave and Expanded FMLA Protections During the Best and Worst of Times

In addition to paid sick days to cover short-term needs, nearly all working men and women will need time away from their jobs at some point to care for a new child or seriously ill loved one or to address their own serious health condition. Tens of millions of workers cannot afford to take the time they need without some wage replacement, and H.R 1406 would do nothing to address this urgent need. It does not even offer a guarantee that an expecting parent who planned carefully for time away from work to welcome a new child to the family or a sister who wants to help a sibling through cancer treatment would be able to take banked comp time to meet those needs. Despite rhetoric to the contrary, H.R. 1406 would not even ensure that a parent who wanted to use banked comp time to attend a parent-teacher conference would have that leave request granted.

As prominent current and former lawmakers on both sides of the political aisle have noted recently in conjunction with the 20th anniversary of the Family and Medical Leave Act, it is time for the United States to adopt a national system of paid family and medical leave insurance and to expand unpaid, job-protected FMLA leave to cover more workers who need leave for more reasons.

Only 11 percent of private sector workers have designated paid family leave through their employers, and fewer than 40 percent have personal short-term disability insurance through an employer-sponsored plan. Only about 50 percent of first-time mothers can cobble together any form of paid leave, whether sick or vacation days, disability insurance, or something else. That number has been stagnant for a decade. Fewer than 20 percent of women with low levels of formal education have access to paid leave and that number has not increased since 1961.

Adopting a national paid family and medical leave insurance program, similar to successful state programs, would: increase families? financial stability; promote better health outcomes for children, elders and caregivers; generate new tax revenues; and reduce burdens on the social safety net. In the year following a birth, new mothers who take paid leave are 54 percent more likely to report wage increases and 39 percent less likely to need public assistance than mothers who do not. Fathers who take paid leave are also less likely to need public assistance. Paid leave also safeguards the income and retirement security of workers with eldercare responsibilities who might otherwise have to drop out of the workforce. On average, a worker who is 50 years of age or older who leaves the workforce to take care of a parent will lose more than $300,000 in wages and retirement income.

To better understand the need for and the potential power of a national paid leave policy solution, we can look to the two states that have created paid leave insurance systems. California created the nation?s first statewide paid family leave insurance program in 2002, and New Jersey followed in 2008. These programs were built upon those states? much older and well-established temporary disability insurance systems, which workers have been using for decades to take leave from work to address their own serious health conditions. Women who use California?s paid family leave program are better able to arrange child care and to breastfeed their children for longer, both of which are associated with improved child well-being. Men are more likely to take leave now, sharing more equally in caregiving responsibilities with women. And California employers have been able to implement the program smoothly. About 60 percent have been able to coordinate their own benefits with the state program, which has likely led to cost savings. We believe this provides a model for a national paid family leave program.

For 20 years, the Family and Medical Leave Act has been an unqualified success, helping mothers and fathers, sons and daughters, and husbands and wives to take leave more than 100 million times. But according to the most recent Department of Labor data, slightly less than 60 percent of the workforce is eligible for FMLA leave, leaving tens of millions of workers vulnerable to job loss when family or personal needs arise. The comp time offered by H.R. 1406 would not fill this gap for workers who are not covered by the FMLA, despite rhetoric to the contrary.

The FMLA should be updated. We need to extend its protections to employees in smaller businesses and to those who work part-time. The definition of ?family member? should be updated to allow workers to take FMLA leave to care for a domestic partner, parent-in-law, adult child, sibling, grandchild or grandparent. Such an expansion would have allowed Anne-Marie Pearson, a conscientious worker in Pennsylvania, to have cared for her dying sister without having to leave her job. Similarly, it would help countless others care for close relatives in their final days.

Expanding the FMLA in this way would not unduly burden employers. The vast majority of businesses report that complying with the FMLA has had a positive effect or no noticeable effect on employees and their business. In fact, 37 percent of worksites covered by the FMLA reported that compliance has had a ?positive effect? on ?employee productivity, absenteeism, turnover, career advancement and morale, as well as the business? profitability.? Half (54 percent) said compliance has had ?no noticeable effect.? Many businesses are voluntarily making FMLA leave available to workers who are not covered.

The FMLA?s promise of job protection should also be extended to address more circumstances. For example, H.R. 1406?s sponsor and others have talked about comp time as the solution to a parent?s need to attend a parent-teacher conference. A much more useful policy solution, and one that would help many more parents and children, is a ?small necessities? expansion of the FMLA so that workers could take up to 24 hours per year to attend school meetings, parent-teacher conferences and other essential educational activities. Separately, victims of domestic violence should be able to use FMLA leave to seek legal, medical and relocation services.

True Flexibility Would Reflect Employees? Needs for Predictability, Notice and Fluidity in Scheduling as Well as the Right to Refuse Overtime

H.R. 1406 has the word ?flexibility? in its title, but the flexibility it offers workers is an empty promise. A growing body of research shows that true flexibility and predictability the ability to vary start and ending times, to work split shifts, and to have advance notice of scheduling provides benefits for workers and cost-savings for employers. Nothing in the FLSA prohibits these best practices.

It should be a priority to educate employers about the flexibility available under the FLSA and the benefits that flexibility provides. We should create disincentives for scheduling practices such as ?just in time? scheduling and call-in shifts, which hold workers back, impede their productivity on the job, interfere with their caregiving responsibilities at home and create extra child care and transportation expenses. Public policies should protect workers who cannot work mandatory overtime and should offer protections to those who report to work or put other job opportunities on hold only to find out that they are not needed when they arrive at the job site. Policies that encourage predictability and advance notice, and discourage rigidity, are also needed.

Conclusion

At a time when our nation?s working families urgently need public policies that make our workplaces more fair and family friendly, H.R. 1406 is an empty promise a cruel hoax that would take the country in the wrong direction. It would make life appreciably harder for families that are already struggling, and no amount of misleading or deceptive rhetoric can soften the blow. For many workers, H.R. 1406 would bring less pay, less flexibility and workplaces that are even less family friendly.

Instead of wasting time on smoke and mirrors to try to hide the real impact of this bill, I urge you instead to support the Healthy Families Act, paid family and medical leave insurance, expanded access to the FMLA, the Fair Minimum Wage Act, the Paycheck Fairness Act and proposals to encourage fairer, more predictable and more flexible work hours. These are the advances the nation needs. These are and the initiatives that would help our nation?s workers and their families, employers, communities and our economy.

Chairman Walberg, Ranking Member Courtney and members of the Committee, thank you for the opportunity to testify here today. With our many allies, and on behalf of America?s workers, the National Partnership for Women & Families looks forward to working with you to adopt policies that are truly family friendly.

A PDF version of this testimony that includes citations can be found here.

The National Partnership for Women & Families is a non-profit, non-partisan advocacy group dedicated to promoting fairness in the workplace, access to quality health care and policies that help women and men meet the dual demands of work and family.

Source: http://www.nationalpartnership.org/site/News2?page=NewsArticle&id=39009

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